Bioactive Phenolic and Isocoumarin Glycosides from the Stems of Homalium paniculiflorum.
نویسندگان
چکیده
Two new phenolic glycosides (1 and 2) and two new isocoumarin glycosides (3 and 4), along with 14 known compounds (5-18), were isolated from the stems of Homalium paniculiflorum. Their structures were established on the basis of extensive spectroscopic analyses and chemical methods. All new compounds were evaluated for their anti-inflammatory activities via examining the inhibitory activity on nitric oxide (NO) production induced by lipopolysaccharide (LPS) in mouse macrophage RAW 264.7 cells in vitro. Compounds 1 and 4 exhibited inhibitory activities with IC50 values of 30.23 ± 1.23 μM and 19.36 ± 0.19 μM, respectively.
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عنوان ژورنال:
- Molecules
دوره 23 2 شماره
صفحات -
تاریخ انتشار 2018